I have read other similar posts before, but I quite like what he wrote:
Below are some of my favorites / reminders (on things I need to improve on):
2) Life is not a dress rehearsal—this is probably it. Make it count. Time is extremely limited and goes by fast. Do what makes you happy and fulfilled—few people get remembered hundreds of years after they die anyway. Don’t do stuff that doesn’t make you happy (this happens most often when other people want you to do something). Don’t spend time trying to maintain relationships with people you don’t like, and cut negative people out of your life. Negativity is really bad. Don’t let yourself make excuses for not doing the things you want to do.
6) Talk to people more. Read more long content and less tweets. Watch less TV. Spend less time on the Internet.
8) Don’t let yourself get pushed around. As Paul Graham once said to me, “People can become formidable, but it’s hard to predict who”. (There is a big difference between confident and arrogant. Aim for the former, obviously.)
11) Go out of your way to be around smart, interesting, ambitious people. Work for them and hire them (in fact, one of the most satisfying parts of work is forging deep relationships with really good people). Try to spend time with people who are either among the best in the world at what they do or extremely promising but totally unknown. It really is true that you become an average of the people you spend the most time with.
16) Ask for what you want.
23) Learn voraciously.
24) Do new things often. This seems to be really important. Not only does doing new things seem to slow down the perception of time, increase happiness, and keep life interesting, but it seems to prevent people from calcifying in the ways that they think. Aim to do something big, new, and risky every year in your personal and professional life.